Gingipain K Explained

Gingipain K
Ec Number:3.4.22.47
Cas Number:159745-69-4

Gingipain K (Lys-gingipain, PrtP proteinase) is an enzyme.[1] [2] This enzyme catalyses the following chemical reaction

Endopeptidase with strict specificity for lysyl bonds

Activity of this enzyme is stimulated by glycine.

See also

Notes and References

  1. Pike R, McGraw W, Potempa J, Travis J . Lysine- and arginine-specific proteinases from Porphyromonas gingivalis. Isolation, characterization, and evidence for the existence of complexes with hemagglutinins . The Journal of Biological Chemistry . 269 . 1 . 406–11 . January 1994 . 8276827 .
  2. Curtis MA, Aduse Opoku J, Rangarajan M, Gallagher A, Sterne JA, Reid CR, Evans HE, Samuelsson B . Attenuation of the virulence of Porphyromonas gingivalis by using a specific synthetic Kgp protease inhibitor . Infection and Immunity . 70 . 12 . 6968–75 . December 2002 . 12438376 . 132948 . 10.1128/iai.70.12.6968-6975.2002 .