Geranylgeraniol 18-hydroxylase explained

Geranylgeraniol 18-hydroxylase
Ec Number:	1.14.13.110

Geranylgeraniol 18-hydroxylase (GGOH-18-hydroxylase) is an enzyme with systematic name geranylgeraniol,NADPH:oxygen oxidoreductase (18-hydroxylating).^[1] This enzyme catalyses the following chemical reaction

geranylgeraniol + NADPH + H⁺ + O₂

\rightleftharpoons 18-hydroxygeranylgeraniol + NADP⁺ + H₂O

Geranylgeraniol 18-hydroxylase is a heme-thiolate protein (P-450).

Notes and References

1. Geranylgeraniol-18-hydroxylase: the last enzyme in the plaunotol biosynthetic pathway in Croton sublyratus . Tansakul P, De-Eknamkul W . Phytochemistry . 1998 . 47 . 7 . 1241–1246 . 10.1016/s0031-9422(97)00743-7.