Geranyl diphosphate 2-C-methyltransferase explained
| Geranyl diphosphate 2-C-methyltransferase |
| Ec Number: | 2.1.1.255 |
Geranyl diphosphate 2-C-methyltransferase (SCO7701, GPP methyltransferase, GPPMT, 2-methyl-GPP synthase, MGPPS, geranyl pyrophosphate methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:geranyl-diphosphate 2-C-methyltransferase.[1] [2] [3] [4] This enzyme catalyses the following chemical reaction
S-adenosyl-L-homocysteine + (E)-2-methylgeranyl diphosphate
This enzyme takes part in synthesis of 2-methylisoborneol.
Notes and References
- Wang CM, Cane DE . Biochemistry and molecular genetics of the biosynthesis of the earthy odorant methylisoborneol in Streptomyces coelicolor . Journal of the American Chemical Society . 130 . 28 . 8908–9 . July 2008 . 18563898 . 3023297 . 10.1021/ja803639g .
- Ariyawutthiphan O, Ose T, Tsuda M, Gao Y, Yao M, Minami A, Oikawa H, Tanaka I . Crystallization and preliminary X-ray crystallographic study of a methyltransferase involved in 2-methylisoborneol biosynthesis in Streptomyces lasaliensis . Acta Crystallographica Section F . 67 . Pt 3 . 417–20 . March 2011 . 21393856 . 3053176 . 10.1107/s1744309110051523 .
- Komatsu M, Tsuda M, Omura S, Oikawa H, Ikeda H . Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol . Proceedings of the National Academy of Sciences of the United States of America . 105 . 21 . 7422–7 . May 2008 . 18492804 . 2387273 . 10.1073/pnas.0802312105 . free .
- Giglio S, Chou WK, Ikeda H, Cane DE, Monis PT . Biosynthesis of 2-methylisoborneol in cyanobacteria . Environmental Science & Technology . 45 . 3 . 992–8 . February 2011 . 21174459 . 3699865 . 10.1021/es102992p .
