Genotype–phenotype map explained
The genotype–phenotype map is a conceptual model in genetic architecture. Coined in a 1991 paper by Pere Alberch,[1] it models the interdependency of genotype (an organism's full hereditary information) with phenotype (an organism's actual observed properties).
Application
The map visualises a relationship between genotype & phenotype which, crucially:[2]
- is of greater complexity than a straightforward one-to-one mapping of genotype to/from phenotype.
- accommodates a parameter space, along which at different points a given phenotype is said to be more or less stable.
- accommodates transformational boundaries in the parameter space, which divide phenotype states from one another.
- accounts for different polymorphism and/or polyphenism in populations, depending on their area of parameter space they occupy.
See also
Notes and References
- From genes to phenotype: dynamical systems and evolvability . Alberch . Pere . Genetica . 1991 . 84 . 1 . 5–11 . 10.1007/BF00123979 . 1874440 . 28286781 . 18 October 2020.
- Genotype–phenotype mapping and the end of the 'genes as blueprint' metaphor . Pigliucci . Massimo . Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences . 2010 . 365 . 1540 . 557–566 . 10.1098/rstb.2009.0241 . 20083632 . 2817137 .
