Gamma-Renin Explained

Gamma-renin
Ec Number:3.4.21.54
Cas Number:85270-20-8

Gamma-renin is an enzyme.[1] [2] This enzyme catalyses the following chemical reaction

Cleavage of the Leu-Leu bond in synthetic renin substrate (horse), to produce angiotensin I, but not active on natural angiotensinogen

This enzyme is present in submandibular glands of male mice.

Notes and References

  1. Poe M, Wu JK, Florance JR, Rodkey JA, Bennett CD, Hoogsteen K . Purification and properties of renin and gamma-renin from the mouse submaxillary gland . The Journal of Biological Chemistry . 258 . 4 . 2209–16 . February 1983 . 6337154 .
  2. Drinkwater CC, Evans BA, Richards RI . Sequence and expression of mouse gamma-renin . The Journal of Biological Chemistry . 263 . 18 . 8565–8 . June 1988 . 3288617 .