Galactosylceramide sulfotransferase explained

galactosylceramide sulfotransferase
Ec Number:2.8.2.11
Cas Number:9081-06-5
Go Code:0001733

In enzymology, a galactosylceramide sulfotransferase is an enzyme that catalyzes the chemical reaction

3'-phosphoadenylyl sulfate + a galactosylceramide

\rightleftharpoons

adenosine 3',5'-bisphosphate + a galactosylceramidesulfate

Thus, its two substrates are 3'-phosphoadenylyl sulfate and galactosylceramide, and its two products are adenosine 3',5'-bisphosphate and galactosylceramidesulfate.

It belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:galactosylceramide 3'-sulfotransferase. Other names in common use include GSase, 3'-phosphoadenosine-5'-phosphosulfate-cerebroside sulfotransferase, galactocerebroside sulfotransferase, galactolipid sulfotransferase, glycolipid sulfotransferase, and glycosphingolipid sulfotransferase. This enzyme participates in sphingolipid metabolism.

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