Galactose 1-dehydrogenase (NADP+) explained
| galactose 1-dehydrogenase (NADP+) |
| Ec Number: | 1.1.1.120 |
| Cas Number: | 37250-51-4 |
| Go Code: | 0047910 |
In enzymology, a galactose 1-dehydrogenase (NADP+) is an enzyme that catalyzes the chemical reaction
D-galactose + NADP+
D-galactono-1,5-lactone + NADPH + H
+Thus, the two substrates of this enzyme are D-galactose and NADP+, whereas its 3 products are D-galactono-1,5-lactone, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-galactose:NADP+ 1-oxidoreductase. Other names in common use include D-galactose dehydrogenase (NADP+), and galactose 1-dehydrogenase (NADP+). This enzyme participates in galactose metabolism.
References
- Cline AL, Hu AS . 1965 . The isolation of three sugar dehydrogenases from a . J. Biol. Chem. . 240 . 4488–92 . 5845847 . 11 .
- Cline AL, Hu AS . 1965 . Enzymatic characterization and comparison of three sugar dehydrogenases from a pseudomonad . J. Biol. Chem. . 240 . 4493–7 . 5845848 . 11 .
- Cline AL, Hu AS . 1965 . Some physical properties of three sugar dehydrogenases from a pseudomonad . J. Biol. Chem. . 240 . 4498–502 . 5845849 . 11 .
- Schiwara HW, Domagk GF . 1968 . Über den Abbau der Desoxyzucker durch Bakterienenzyme, V. Anreicherung und Charakterisierung einer NADP-abhängigen Abequosedehydrogenase aus Pseudomonas putida . Degradation of deoxysurgars by bacterial enzymes. V. Purification and characterization of an NADP-dependent abequose dehydrogenase from Pseudomonas putida . German . Hoppe-Seyler's Z. Physiol. Chem. . 349 . 1321–9 . 4387016 . 10 . 10.1515/bchm2.1968.349.2.1321.
