Galactitol-1-phosphate 5-dehydrogenase explained

galactitol-1-phosphate 5-dehydrogenase
Ec Number:	1.1.1.251
Cas Number:	167618-25-9
Go Code:	0008868

In enzymology, a galactitol-1-phosphate 5-dehydrogenase is an enzyme that catalyzes the chemical reaction

galactitol-1-phosphate + NAD⁺

\rightleftharpoons L-tagatose 6-phosphate + NADH + H⁺

Thus, the two substrates of this enzyme are galactitol-1-phosphate and NAD⁺, whereas its 3 products are L-tagatose 6-phosphate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is galactitol-1-phosphate:NAD⁺ oxidoreductase. This enzyme participates in galactose metabolism. It employs one cofactor, zinc.

References

• Nobelmann B, Lengeler JW . 1995 . Sequence of the gat operon for galactitol utilization from a wild-type strain EC3132 of Escherichia coli . Biochim. Biophys. Acta . 1262 . 69 - 72 . 7772602 . 1 . 10.1016/0167-4781(95)00053-j.