| γ-Glutamylhistamine synthase | |
| Ec Number: | 6.3.2.18 |
| Cas Number: | 82904-08-3 |
| Go Code: | 0047914 |
In enzymology, a γ-glutamylhistamine synthase is an enzyme that catalyzes the chemical reaction
ATP + L-glutamate + histamine
\rightleftharpoons
The 3 substrates of this enzyme are ATP, L-glutamate, and histamine, whereas its two products are products of ATP breakdown and Nalpha-gamma-L-glutamylhistamine.
This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-amino-acid ligases (peptide synthases). The systematic name of this enzyme class is L-glutamate:histamine ligase. Other names in common use include gamma-glutaminylhistamine synthetase, and gamma-GHA synthetase.