Furylfuramide isomerase explained

furylfuramide isomerase
Ec Number:	5.2.1.6
Cas Number:	72561-07-0
Go Code:	0047907

In enzymology, a furylfuramide isomerase is an enzyme that catalyzes the chemical reaction

\rightleftharpoons (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide

Hence, this enzyme has one substrate, (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide, and one product, (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide.

This enzyme belongs to the family of isomerases, specifically cis-trans isomerases. The systematic name of this enzyme class is 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide cis-trans-isomerase. It has 2 cofactors: NAD+, and NADH.

References

• Tomoeda M, Kitamura R . 1977 . A cis-trans isomerising activity of Escherichia coli. Isomerization from 2-(2-furyl)-3-cis-(5-nitro-2-furyl) acrylamide (furylfuramide) to its trans isomer . Biochim. Biophys. Acta . 480 . 315 - 25 . 12827 . 1 . 10.1016/0005-2744(77)90344-8.