Functio laesa explained

Functio laesa is a term used in medicine to refer to a loss of function[1] [2] or a disturbance of function.[3]

It was identified as the fifth sign of acute inflammation by Galen, who added it to the four signs identified by Celsus (tumor, rubor, calor, and dolor).[4]

The attribution to Galen is disputed,[3] and has variously been attributed to Thomas Sydenham[5] and Rudolf Virchow.[6]

Notes and References

  1. Web site: Dorlands Medical Dictionary:cardinal signs.
  2. Web site: Definition: functio laesa from Online Medical Dictionary .
  3. Rather LJ . Disturbance of function (functio laesa): The legendary fifth cardinal sign of inflammation, added by Galen to the four cardinal signs of Celsus . Bull N Y Acad Med . 47 . 3 . 303–22 . March 1971 . 5276838 . 1749862 .
  4. Book: Porth, Carol . Essentials of pahtophysiology: concepts of altered health states . Lippincott Williams & Wilkins . Hagerstown, MD . 2007 . 270 . 978-0-7817-7087-3 .
  5. Book: Dormandy, Thomas . The worst of evils: man's fight against pain . Yale University Press . New Haven, Conn . 2006 . 22 . 0-300-11322-6 . registration .
  6. Book: David Lowell Strayer . Raphael Rubin . Rubin's Pathology: Clinicopathologic Foundations of Medicine 5th Edition . Lippincott Williams & Wilkins . Hagerstown, MD . 2007 . 37 . 978-0-7817-9516-6 .

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