Formyl-CoA hydrolase explained

formyl-CoA hydrolase
Ec Number:	3.1.2.10
Cas Number:	9025-91-6
Go Code:	0047901

The enzyme formyl-CoA hydrolase (EC 3.1.2.10) catalyzes the reaction

formyl-CoA + H₂O

\rightleftharpoons CoA + formate

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name is formyl-CoA hydrolase. This enzyme is also called formyl coenzyme A hydrolase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

References

• Sly WS, Stadtman ER . Formate metabolism. I. Formyl coenzyme A, an intermediate in the formate-dependent decomposition of acetyl phosphate in Clostridium kluyveri . The Journal of Biological Chemistry . 238 . 2632–8 . August 1963 . 14063284 .