Formimidoylaspartate deiminase explained

formimidoylaspartate deiminase
Ec Number:	3.5.3.5
Cas Number:	9025-07-4
Go Code:	0050414

In enzymology, a formimidoylaspartate deiminase is an enzyme that catalyzes the chemical reaction

N-formimidoyl-L-aspartate + H₂O

\rightleftharpoons N-formyl-L-aspartate + NH₃

Thus, the two substrates of this enzyme are N-formimidoyl-L-aspartate and H₂O, whereas its two products are N-formyl-L-aspartate and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is N-formimidoyl-L-aspartate iminohydrolase. This enzyme is also called formiminoaspartate deiminase. This enzyme participates in histidine metabolism.

References

• HAYAISHI O, TABOR H, HAYAISHI T . 1957 . N-formimino-L-aspartic acid as an intermediate in the enzymatic conversion of imidazoleacetic acid to formylaspartic acid . J. Biol. Chem. . 227 . 161 - 80 . 13449062 . 1 .