Formaldehyde transketolase explained
| formaldehyde transketolase |
| Ec Number: | 2.2.1.3 |
| Cas Number: | 76774-46-4 |
| Go Code: | 0047896 |
In enzymology, a formaldehyde transketolase is an enzyme that catalyzes the chemical reaction
D-xylulose 5-phosphate + formaldehyde
glyceraldehyde 3-phosphate + glycerone
Thus, the two substrates of this enzyme are D-xylulose 5-phosphate and formaldehyde, whereas its two products are glyceraldehyde 3-phosphate and glycerone.
This enzyme belongs to the family of transferases, specifically those transferring aldehyde or ketonic groups (transaldolases and transketolases, respectively). The systematic name of this enzyme class is D-xylulose-5-phosphate:formaldehyde glycolaldehydetransferase. This enzyme is also called dihydroxyacetone synthase. This enzyme participates in methane metabolism. It employs one cofactor, thiamin diphosphate.
References
- Bystrykh . L. V. . A. P. Sokolov . Iu. A. Trotsenko . 1981 . Separation of transketolase and dihydroxyacetone synthase from methylotrophic yeasts . Russian . . 258 . 499 - 501 . 7249920 . Separation of transketolase and dihydroxyacetone synthase from methylotrophic yeasts . 2 .
- Kato N, Higuchi T, Sakazawa C, Nishizawa T, Tani Y, Yamada H . 1982 . Purification and properties of a transketolase responsible for formaldehyde fixation in a methanol-utilizing yeast, candida boidinii (Kloeckera sp.) No. 2201 . Biochim. Biophys. Acta . 715 . 143 - 50 . 7074134 . 2 . 10.1016/0304-4165(82)90352-x.
- Waites MJ, Quayle JR . 1981 . The interrelation transketolase and dihydroxyacetone synthase activities in the methylotrophic yeast Candida boidinii . J. Gen. Microbiol. . 124 . 309 - 16 . 6276498 . 2 . 10.1099/00221287-124-2-309. free .
