4-Fluoro-L-threonine explained

4-Fluoro--threonine is an antibacterial produced by Streptomyces cattleya. It is formed by the fluorothreonine transaldolase catalysed transfer of fluoroacetaldehyde onto threonine.[1]

Notes and References

  1. Murphy CD, O'Hagan D, Schaffrath C . 2001 . Identification of a PLP-Dependent Threonine Transaldolase: A Novel Enzyme Involved in 4-Fluorothreonine Biosynthesis in Streptomyces cattleya This work was supported by the Biotechnological and Biological Sciences Research Council and the University of St Andrews . Angew. Chem. Int. Ed. Engl. . 40 . 4479–4481 . 12404452 . 10.1002/1521-3773(20011203)40:23<4479::AID-ANIE4479>3.0.CO;2-1 . 23.

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