Fletazepam Explained

Fletazepam[1] is a drug which is a benzodiazepine derivative. It has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives, but is mainly notable for its strong muscle relaxant properties.[2]

Fletazepam is most closely related to other N-trifluoroethyl substituted benzodiazepines such as halazepam and quazepam.[3]

See also

Notes and References

  1. DE. 2106175. 1971-09-30. Neue 1-Polyfluoralkylbenzodiazepine und Verfahren zu ihrer Herstellung [Novel 1-polyfluoroalkylbenzodiazepines and processes for their preparation]. Sherico Ltd.. Steinmann. Martin .
  2. Barnett A, Goldstein J, Fiedler EP, Taber RI . The pharmacology of fletazepam a centrally-acting muscle relaxant . Archives Internationales de Pharmacodynamie et de Therapie . 212 . 1 . 164–74 . November 1974 . 4476200 .
  3. Iorio LC, Barnett A, Billard W . Selective affinity of 1-N-trifluoroethyl benzodiazepines for cerebellar type 1 receptor sites . Life Sciences . 35 . 1 . 105–13 . July 1984 . 6738302 . 10.1016/0024-3205(84)90157-7 .

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