Flavonol-3-O-glycoside glucosyltransferase explained

Flavonol-3-O-glycoside glucosyltransferase
Ec Number:	2.4.1.240

In enzymology, a flavonol-3-O-glycoside glucosyltransferase is an enzyme that catalyzes the chemical reaction

UDP-glucose + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside

\rightleftharpoons UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside

Thus, the two substrates of this enzyme are UDP-glucose and flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside, whereas its 3 products are UDP, flavonol, and 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:flavonol-3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside 2-O-beta-D-glucosyltransferase.

References

• Jourdan PS, Mansell RL . 1982 . Isolation and partial characterization of three glucosyl transferases involved in the biosynthesis of flavonol triglucosides in Pisum sativum L . Arch. Biochem. Biophys. . 213 . 434 - 43 . 6462109 . 10.1016/0003-9861(82)90569-0 . 2 .