Flavonoid 4'-O-methyltransferase explained

Flavonoid 4'-O-methyltransferase
Ec Number:	2.1.1.231

Flavonoid 4'-O-methyltransferase (SOMT-2, 4'-hydroxyisoflavone methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase.^[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + 4'-hydroxyflavanone

\rightleftharpoons

S-adenosyl-L-homocysteine + 4'-methoxyflavanone

The enzyme catalyses the 4'-methylation of naringenin.

Notes and References

Kim DH, Kim BG, Lee Y, Ryu JY, Lim Y, Hur HG, Ahn JH . Regiospecific methylation of naringenin to ponciretin by soybean O-methyltransferase expressed in Escherichia coli . Journal of Biotechnology . 119 . 2 . 155–62 . September 2005 . 15961179 . 10.1016/j.jbiotec.2005.04.004 .