Feruloyl esterase explained
| feruloyl esterase |
| Ec Number: | 3.1.1.73 |
| Cas Number: | 134712-49-5 |
| Go Code: | 0030600 |
The enzyme feruloyl esterase (EC 3.1.1.73) catalyzes the reaction
feruloyl-polysaccharide + H2O
ferulate + polysaccharide
This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is 4-hydroxy-3-methoxycinnamoyl-sugar hydrolase. Other names in common use include ferulic acid esterase (FAE), hydroxycinnamoyl esterase, hemicellulase accessory enzyme, cinnamoyl ester hydrolase (cinnAE).
Structural studies
As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes,,,,, and .
References
- Catherine Tomaro-Duchesneau . Shyamali Saha . Meenakshi Malhotra . Michael Coussa-Charley . Imen Kahouli . Mitchell L. Jones . Alain Labbe . Satya Prakash . 2012 . Probiotic Ferulic Acid Esterase Active Lactobacillus fermentum NCIMB 5221 APA Microcapsules for Oral Delivery: Preparation and in Vitro Characterization . Pharmaceuticals . 5 . 236 - 248 . 2 . 10.3390/ph5020236 . 24288090 . 3763630 . free .
- D.B.R.K. Gupta Udatha . Irene Kouskoumvekaki . Lisbeth Olsson . Gianni Panagiotou . 2011 . The interplay of descriptor-based computational analysis with pharmacophore modeling builds the basis for a novel classification scheme for feruloyl esterases . Biotechnology Advances . 29 . 94 - 110 . 20851174 . 1 . 10.1016/j.biotechadv.2010.09.003 .
- Faulds CB, Williamson G . 1991 . The purification and characterization of 4-hydroxy-3-methoxycinnamic (ferulic) acid esterase from Streptomyces olivochromogenes . J. Gen. Microbiol. . 137 . 2339 - 45 . 1663152 . 10 . 10.1099/00221287-137-10-2339. free .
- Faulds CB, Williamson G. 1994 . Purification and characterisation of a ferulic acid esterase (FAE-III) from Aspergillus niger. Specificity for the phenolic moiety and binding to microcrystalline cellulose . Microbiology . 140 . 779 - 787 . 10.1099/00221287-140-4-779 . 4 . free .
- Kroon PA, Faulds CB, Williamson G . June 1996. Purification and characterization of a novel esterase induced by growth of Aspergillus niger on sugar-beet pulp . Biotechnol. Appl. Biochem. . 23 . 3. 255 - 62 . 10.1111/j.1470-8744.1996.tb00381.x. 8679110 . 19514727.
- Faulds CB, Williamson G, van den Hombergh JP, Visser J . 1997 . The faeA genes from Aspergillus niger and Aspergillus tubingensis encode ferulic acid esterases involved in degradation of complex cell wall polysaccharides . Appl. Environ. Microbiol. . 63 . 4638 - 44 . 9406381 . 12 . 10.1128/AEM.63.12.4638-4644.1997 . 168785 .
- Castanares A, Mccrae SI, Wood TM . 1992 . Purification and properties of a feruloyl/p-coumaroyl esterase from the fungus Penicillium pinophilum . Enzyme and Microbial Technology . 14 . 875 - 884 . 10.1016/0141-0229(92)90050-X . 11 .
