Fenamic acid explained

Fenamic acid is an organic compound, which, especially in its ester form, is called fenamate.^[1] serves as a parent structure for several nonsteroidal anti-inflammatory drugs (NSAIDs), including mefenamic acid, tolfenamic acid, flufenamic acid, and meclofenamic acid. These drugs are commonly referred to as "anthranilic acid derivatives" or "fenamates" because fenamic acid is a derivative of anthranilic acid.^{[2] [3] [2]}

Fenamic acid can be synthesized from 2-chlorobenzoic acid and can be converted into acridone.^[4]

Notes and References

1. Gupta, PK. Drug NomenclatureUnited States Adopted Names. Ch 27 in Remington: The Science and Practice of Pharmacy, Vol 1. Eds. David B. Troy, Paul Beringer. Lippincott Williams & Wilkins, 2006
2. Sriram D, Yogeeswari P. Medicinal Chemistry, 2nd Edition. Pearson Education India, 2010.
3. Auburn University course material. Jack DeRuiter, Principles of Drug Action 2, Fall 2002 1: Non-Steroidal Antiinflammatory Drugs (NSAIDS)
4. Acridone . C. F. H. Allen, G. H. W. McKee . Organic Syntheses . 2 . 6. 10.15227/orgsyn.019.0006. 1939.