Ezetimibe/rosuvastatin explained

Type:combo
Width:275
Component1:Ezetimibe
Class1:Hypolipidemic agent
Component2:Rosuvastatin
Class2:Statin
Tradename:Ridutrink, Roszet, others
Dailymedid:Ezetimibe and rosuvastatin
Pregnancy Au:D
Routes Of Administration:By mouth
Atc Prefix:C10
Atc Suffix:BA06
Legal Au:S4
Legal Au Comment:[1] [2]
Legal Us:Rx-only
Legal Us Comment:[3]
Legal Eu:Rx-only
Legal Eu Comment:[4]
Legal Status:Rx-only
Kegg:D11520

Ezetimibe/rosuvastatin, sold under the brand name Ridutrin among others, is a combination medication used to treat high cholesterol.[5] [6] In some countries it is sold as a kit or a pack containing two distinct pills.[7] [8]

The combination was approved for medical use in the United States in March 2021.

Medical uses

Ezetimibe/rosuvastatin is indicated as an adjunct to diet in people with primary non-familial hyperlipidemia to reduce low-density lipoprotein cholesterol (LDL-C); and alone or as an adjunct to other LDL-C-lowering therapies in people with homozygous familial hypercholesterolemia (HoFH) to reduce LDL-C.[9]

Pharmacology

Ezetimibe/rosuvastatin combines two lipid-lowering therapies.

External links

Notes and References

  1. Web site: TGA eBS - Product and Consumer Medicine Information Licence. 25 March 2021. 29 March 2022. https://web.archive.org/web/20220329081946/https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2013-PI-02443-1. live.
  2. Web site: EZESTAT COMPOSITE PACK (Pharmacor Pty Ltd) . . https://web.archive.org/web/20230318024929/https://www.tga.gov.au/resources/prescription-medicines-registrations/ezestat-composite-pack-pharmacor-pty-ltd . 18 March 2023 . live.
  3. Web site: Roszet: FDA-Approved Drugs . U.S. Food and Drug Administration (FDA) . 24 March 2021.
  4. Web site: Ezetimibe/rosuvastatin: List of nationally authorised medicinal products . European Medicines Agency (EMA) . PSUSA/00010271/201707 . 21 March 2018 . 17 February 2020 .
  5. Web site: Ridutrin SmPC . Medicines Data Bank . 30 May 2019 . 17 February 2020 . 18 February 2020 . https://web.archive.org/web/20200218073308/https://www.geneesmiddeleninformatiebank.nl/smpc/h114010_smpc_en.pdf . live .
  6. Book: Willihnganz MJ, Gurevitz SL, Clayton BD . HMG-CoA Reductase Inhibitor Combination Products . https://books.google.com/books?id=sklSEAAAQBAJ&pg=PA344 . Clayton's Basic Pharmacology for Nurses - E-Book . November 2021 . Elsevier Health Sciences . 978-0-323-81258-0 . 344.
  7. Web site: Rosuzet Composite Pack . NPS MedicineWise . 8 January 2020 . 17 February 2020 . 18 February 2020 . https://web.archive.org/web/20200218075145/https://www.nps.org.au/medicine-finder/rosuzet-composite-pack-10-mg-10-mg-tablets . live .
  8. Web site: Rosuvastatin international . Drugs.com . 3 February 2020 . 17 February 2020 . 18 February 2020 . https://web.archive.org/web/20200218073306/https://www.drugs.com/international/rosuvastatin.html . live .
  9. Web site: Sharretts J . NDA Approval Letter for Roszet (rosuvastatin and ezetimibe) . U.S. Food and Drug Administration . 23 March 2021 . 25 March 2021 . 7 April 2023 . https://web.archive.org/web/20230407150710/https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2021/213072Orig1s000ltr.pdf . live .
  10. Web site: DailyMed - Roszet- rosuvastatin and ezetimibe tablet Roszet (- rosuvastatin and ezetimibe tablet . 14 January 2024 . dailymed.nlm.nih.gov . 14 August 2022 . https://web.archive.org/web/20220814023845/https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1653b3c4-2b2a-408b-918a-c687918c6265 . live .

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