Etoxeridine Explained

Etoxeridine (Carbetidine, Atenos) is a 4-phenylpiperidine derivative that is related to the clinically used opioid analgesic drug pethidine (meperidine).

Etoxeridine was developed in the 1950s[1] and investigated for use in surgical anesthesia, however it was never commercialized and is not currently used in medicine.[2] [3] [4] As with other opioids which were not in clinical use during the drafting of the Controlled Substances Act, it is categorized as a Schedule I narcotic.

Notes and References

  1. BE . 558883.
  2. Merlevede E, Levis S . Pharmacological study of carbetidine, a new synthetic analgesic . French . Archives Internationales de Pharmacodynamie et de Thérapie . 1958 . 115 . 1–2 . 213–232. 13545901 .
  3. Sironi PG . Brief note on a new synthetic analgesic: carbetidine hydrochloride . Italian . Minerva Anestesiologica . 1959 . 25 . 6 . 251–254 . 13674097 .
  4. Crawford JS, Foldes FF . Studies on the respiratory and circulatory effects of carbetidine HCI used for supplementation of thiopentone sodium-nitrous oxide-oxygen anaesthesia . British Journal of Anaesthesia . 31 . 8 . 348–51 . August 1959 . 13812715 . 10.1093/bja/31.8.348 . free .

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