Estradiol 3-propionate explained

Estradiol 3-propionate, or 3-propanoylestradiol, also known as estra-1,3,5(10)-triene-3,17β-diol 3-propionate, is a semisynthetic, steroidal estrogen that was never marketed.[1] [2] It is an estrogen ester, specifically, a propionic acid ester of estradiol, and acts as a prodrug to it in vivo. The chemical structure of estradiol 3-propionate is contained within estradiol dipropionate, estrapronicate, and orestrate,[3] all of which are also estradiol esters.

See also

Notes and References

  1. Woolfson AD, Elliott GR, Gilligan CA, Passmore CM . Design of an intravaginal ring for the controlled delivery of 17 beta-estradiol as its 3-acetate ester . J Control Release . 61 . 3 . 319–28 . 1999 . 10477804 . 10.1016/s0168-3659(99)00148-0.
  2. Book: J. Elks. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. 14 November 2014. Springer. 978-1-4757-2085-3. 898.
  3. Web site: PubChem . Estradiol . 2023-11-02 . pubchem.ncbi.nlm.nih.gov . en.

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