Enterobacter ribonuclease explained

Enterobacter ribonuclease
Ec Number:	3.1.27.6
Cas Number:	395640-99-0

Enterobacter ribonuclease is an enzyme.^{[1] [2]} This enzyme catalyses the following chemical reaction

Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates

This enzyme has preference for cleavage at CpA.

Notes and References

1. Levy CC, Goldman P . Residue specificity of a ribonuclease which hydrolyzes polycytidylic acid . The Journal of Biological Chemistry . 245 . 12 . 3257–62 . June 1970 . 10.1016/S0021-9258(18)63048-0 . 5432809 . free .
2. Marotta CA, Levy CC, Weissman SM, Varricchio F . Preferred sites of digestion of a ribonuclease from Enterobacter sp. in the sequence analysis of Bacillus stearothermophilus 5S ribonucleic acid . Biochemistry . 12 . 15 . 2901–4 . July 1973 . 4719125 . 10.1021/bi00739a020 .