Endoglycosylceramidase Explained

endoglycosylceramidase
Ec Number:3.2.1.123
Cas Number:105503-61-5
Go Code:0047876

The enzyme endoglycosylceramidase catalyzes the following chemical reaction:

oligoglycosylglucosylceramide + H2O

\rightleftharpoons

ceramide + oligoglycosylglucose

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name is oligoglycosylglucosylceramide glycohydrolase. Other names in common use include endoglycoceramidase, EGCase, and glycosyl-N-acetyl-sphingosine 1,1-β-D-glucanohydrolase.

Structural studies

As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes,,,,, and .

References