Effacement (histology) explained

Effacement is the shortening, or thinning, of a tissue.

It can refer to cervical effacement. It can also refer to a process occurring in podocytes in nephrotic syndrome.^[1]

In histopathology, it refers to the near obliteration of a tissue, as in the normal parenchyma of tissues in the case of some cancers.

Notes and References

1. Wagner MC, Rhodes G, Wang E, etal . Ischemic injury to kidney induces glomerular podocyte effacement and dissociation of slit diaphragm proteins Neph1 and ZO-1 . J. Biol. Chem. . 283 . 51 . 35579–89 . December 2008 . 18922801 . 2602882 . 10.1074/jbc.M805507200 . free .