See also: List of counts and dukes of Vendôme.
| Picture | Name | Father | Birth | Marriage | Became Duchess | Ceased to be Duchess | Death | Husband |
|---|---|---|---|---|---|---|---|---|
| Françoise d'Alençon | René, Duke of Alençon (Alençon) | 1491 | 18 May 1513 | 6 March 1516 husband's became Duke | 25 March 1537 husband's death | 14 September 1550 | Charles | |
| Jeanne III of Navarre | Henry II of Navarre (Albret) | 16 November 1528 | 20 October 1548 | 17 November 1562 husband's death | 9 June 1572 | Antoine | ||
| Marguerite of France [1] [2] | Henry II of France (Valois) | 14 May 1553 | 18 August 1572 | 17 December 1599 divorce | 27 March 1615 | Henri | ||
| Françoise de Lorraine [3] [4] [5] | Philippe Emmanuel, Duke of Mercœur (Lorraine) | November 1592 | 16 July 1609 | 22 October 1665 husband's death | 8 September 1669 | César | ||
| Marie Anne de Bourbon | Henri Jules, Prince of Condé (Bourbon) | 24 February 1678 | 21 May 1710 | 11 June 1712 husband's death | 11 April 1718 | Louis Joseph | ||
| Marie Joséphine of Savoy [6] [7] [8] | Victor Amadeus III of Savoy (Savoy) | 2 September 1753 | 16 April 1771 | 1790 ceased to be duchess | 13 November 1810 | Louis Stanislas Xavier | ||
| Picture | Name | Father | Birth | Marriage | Became Duchess | Ceased to be Duchess | Death | Husband |
|---|---|---|---|---|---|---|---|---|
| Princess Henriette of Belgium | Prince Philippe, Count of Flanders (Saxe-Coburg and Gotha) | 30 November 1870 | 12 February 1896 | 1 February 1931 | 28 March 1948 | Prince Emmanuel | ||
| Philomena de Tornos Steinhart | Alfonso de Tornos y Zubiría (Tornos) | 19 June 1977 | 19 March 2009 | Incumbent | Prince Jean | |||