Dolichylphosphate-mannose phosphodiesterase explained

dolichylphosphate-mannose phosphodiesterase
Ec Number:	3.1.4.49
Cas Number:	111839-07-7
Go Code:	0047398

The enzyme dolichylphosphate-mannose phosphodiesterase (EC 3.1.4.49)^[1] catalyzes the reaction

dolichyl β-D-mannosyl phosphate + H₂O

\rightleftharpoons dolichyl phosphate + D-mannose

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name is dolichyl-β-D-mannosyl-phosphate dolichylphosphohydrolase. This enzyme is also called mannosylphosphodolichol phosphodiesterase.

Notes and References

1. Tomita Y, Motokawa Y . 1987 . Characterization and partial purification of a novel mannosylphosphodolichol phosphodiesterase from chicken liver microsomes . Eur. J. Biochem. . 170 . 363 - 8 . 2826159 . 10.1111/j.1432-1033.1987.tb13708.x . 1–2 . free .