Dolichyl-diphosphate—polyphosphate phosphotransferase explained

dolichyl-diphosphate-polyphosphate phosphotransferase
Ec Number:	2.7.4.20
Cas Number:	94949-27-6
Go Code:	0047337

In enzymology, a dolichyl-diphosphate-polyphosphate phosphotransferase is an enzyme that catalyzes the chemical reaction

dolichyl diphosphate + (phosphate)n

\rightleftharpoons dolichyl phosphate + (phosphate)n⁺1

Thus, the two substrates of this enzyme are dolichyl diphosphate and (phosphate)n, whereas its two products are dolichyl phosphate and (phosphate)n+1.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a phosphate group as acceptor. The systematic name of this enzyme class is dolichyl-diphosphate:polyphosphate phosphotransferase. This enzyme is also called dolichylpyrophosphate:polyphosphate phosphotransferase.

References

• Naumov AV, Shabalin YA, Vagabov VM, Kulaev IS . Moscow . Two pathways of dephosphorylation of dolichyl diphosphate in yeasts . Biochemistry . 50 . 551 - 556 .