Dobesilic acid explained

Dobesilic acid is a chemical compound with the molecular formula . It is classified as both a phenol and a sulfonic acid.

Uses

Salts of dobesilic are used as pharmaceutical drugs. The calcium salt, calcium dobesilate, is used as a vasoprotective drug.[1] [2] The diethylamine salt, etamsylate, is an antihemorrhagic agent.[3]

Notes and References

  1. Zhang X, Liu W, Wu S, Jin J, Li W, Wang N . Calcium dobesilate for diabetic retinopathy: a systematic review and meta-analysis . Science China Life Sciences . 58 . 1 . 101–7 . January 2015 . 25528255 . 10.1007/s11427-014-4792-1 . free .
  2. Haller H, Ji L, Stahl K, Bertram A, Menne J . Molecular Mechanisms and Treatment Strategies in Diabetic Nephropathy: New Avenues for Calcium Dobesilate-Free Radical Scavenger and Growth Factor Inhibition . BioMed Research International . 2017 . 1909258 . 2017 . 29082239 . 5634607 . 10.1155/2017/1909258 . free .
  3. Schulte J, Osborne J, Benson JW, Cooke R, Drayton M, Murphy J, Rennie J, Speidel B . 6 . Developmental outcome of the use of etamsylate for prevention of periventricular haemorrhage in a randomised controlled trial . Archives of Disease in Childhood. Fetal and Neonatal Edition . 90 . 1 . F31–F35 . January 2005 . 15613570 . 1721806 . 10.1136/adc.2003.035790 .

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