Divinyl chlorophyllide a 8-vinyl-reductase explained

Divinyl chlorophyllide a 8-vinyl-reductase
Ec Number:	1.3.1.75

In enzymology, divinyl chlorophyllide a 8-vinyl-reductase is an enzyme that catalyzes the chemical reaction

3,8-divinylprotochlorophyllide + NADPH + H⁺

\rightleftharpoons protochlorophyllide + NADP⁺

The three substrates of this enzyme are 3,8-divinylprotochlorophyllide, NADPH, and H⁺; its two products are protochlorophyllide and NADP⁺. This enzyme can also convert alternative substrates, for example 3,8-divinyl chlorophyllide a and in all cases reduces a single specific vinyl group to an ethyl group.

This enzyme belongs to the family of oxidoreductases. The systematic name of this enzyme class is chlorophyllide-a :NADP+ oxidoreductase. Other names in common use include 3,8-divinyl protochlorophyllide a 8-vinyl-reductase, [4-vinyl]chlorophyllide a reductase, and 4VCR. This enzyme is part of the biosynthetic pathway to chlorophylls.

See also

• Biosynthesis of chlorophylls

References

• Tripathy BC . Rebeiz CA . 1988 . Chloroplast biogenesis 60. Conversion of divinyl protochlorophyllide to monovinyl protochlorophyllide in green(ing) barley, a dark monovinyl/light divinyl plant species . Plant Physiol. . 87 . 89 - 94 . 10.1104/pp.87.1.89 . 1054704 . 16666133.
• Parham R, Rebeiz CA . 1992 . Chloroplast biogenesis: [4-vinyl] chlorophyllide a reductase is a divinyl chlorophyllide a-specific, NADPH-dependent enzyme . Biochemistry . 31 . 8460 - 4 . 1390630 . 10.1021/bi00151a011 . 36 .
• Parham R, Rebeiz CA . 1995 . Chloroplast biogenesis 72: a [4-vinyl]chlorophyllide a reductase assay using divinyl chlorophyllide a as an exogenous substrate . Anal. Biochem. . 231 . 164 - 9 . 8678296 . 10.1006/abio.1995.1516 . 1 .
• Kolossov VL, Rebeiz CA . 2001 . Chloroplast biogenesis 84: solubilization and partial purification of membrane-bound [4-vinyl]chlorophyllide a reductase from etiolated barley leaves . Anal. Biochem. . 295 . 214 - 9 . 11488624 . 10.1006/abio.2001.5195 . 2 .
• Biosynthesis of chlorophylls from protoporphyrin IX . Willows . Robert D. . Natural Product Reports . 2003 . 20 . 6 . 327–341 . 10.1039/B110549N . 12828371.
• 10.1007/s11120-006-9076-6 . Recent advances in chlorophyll biosynthesis . 2007 . Bollivar . David W. . Photosynthesis Research . 90 . 2 . 173–194 . 17370354 .