Disulfoglucosamine-6-sulfatase explained

disulfoglucosamine-6-sulfatase
Ec Number:	3.1.6.11
Cas Number:	37288-32-7
Go Code:	0047871

The enzyme disulfoglucosamine-6-sulfatase (EC 3.1.6.1)^[1] catalyzes the reaction

2-N,6-O-disulfo-D-glucosamine + H₂O

\rightleftharpoons 2-N-sulfo-D-glucosamine + sulfate

This enzyme belongs to the family of hydrolases, specifically those acting on sulfuric ester bonds. The systematic name is 2-N,6-O-disulfo-D-glucosamine 6-sulfohydrolase. Other names in common use include N-sulfoglucosamine-6-sulfatase, and 6,N-disulfoglucosamine 6-O-sulfohydrolase.

Notes and References

1. Dietrich CP . Enzymic degradation of heparin. A sulphamidase and a sulphoesterase from Flavobacterium heparinum . The Biochemical Journal . 111 . 1 . 91–5 . January 1969 . 5775690 . 1187498 .