Dimenoxadol Explained

Dimenoxadol (INN) (brand name Estocin (in Russia)), or dimenoxadole (BAN), is an opioid analgesic which is a benzilic acid derivative, closely related to benactyzine (an anticholinergic). Further, the structure is similar to methadone and related compounds like dextropropoxyphene.

It was invented in Germany in the 1950s,^[1] and produces similar effects to other opioids, including analgesia, sedation, dizziness and nausea.^{[2] [3] [4]}

In the United States it is a Schedule I Narcotic controlled substance with an ACSCN of 9617 and a 2013 annual aggregate manufacturing quota of zero.

Notes and References

1. GB . 716700 . A new and improved analgesic and process for its production . Boehringer A, et al. . 10/13/1954.
2. Gorbatova EN . [The pharmacology of estocin, an new analgesic] . Stomatologiia . 46 . 2 . 22–5 . 1967 . 5232927 .
3. Kingisepp GI, Kurvits K, Nurmand LB . [Pharmacology of dimethylaminoethyl ester of diphenylethoxyacetic acid hydrochloride--estocin] . Farmakologiia I Toksikologiia . 32 . 6 . 710–2 . 1969 . 5381602 .
4. Liberman SS . [Analgesic action of estocin (dimethylaminoethyl ester hydrochloride of alpha, alpha-diphenylethoxyacetic acid)] . Farmakologiia I Toksikologiia . 31 . 6 . 668–71 . 1968 . 5729519 .