Dihydrobunolol dehydrogenase explained

dihydrobunolol dehydrogenase
Ec Number:1.1.1.160
Cas Number:62213-61-0
Go Code:0047855

In enzymology, a dihydrobunolol dehydrogenase is an enzyme that catalyzes the chemical reaction

(+/−)-5-[(tert-butylamino)-2'-hydroxypropoxy]-1,2,3,4-tetrahydro-1- naphthol + NADP+

\rightleftharpoons

(+/−)-5-[(tert-butylamino)-2'-hydroxypropoxy]-3,4-dihydro-1(2H)- naphthalenone + NADPH + H+

The three substrates of this enzyme are (+/−)-5-[(tert-butylamino)-2'-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol, and NADP+, whereas its 4 products are (+/−)-5-[(tert-butylamino)-2'-hydroxypropoxy]-3,4-dihydro-1(2H)-, naphthalenone, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (+/−)-5-[(tert-butylamino)-2'-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol:NADP+ oxidoreductase. This enzyme is also termed bunolol reductase.

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