Digalactosyldiacylglycerol synthase explained
| digalactosyldiacylglycerol synthase |
| Ec Number: | 2.4.1.241 |
| Go Code: | 0046481 |
In enzymology, a digalactosyldiacylglycerol synthase is an enzyme that catalyzes the chemical reaction
UDP-galactose + 3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol
UDP + 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn- glycerol
Thus, the two substrates of this enzyme are UDP-galactose and 3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol, whereas its 3 products are UDP, 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-, and glycerol.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol 6-alpha-galactosyltransferase. Other names in common use include DGD1, DGD2, DGDG synthase (ambiguous), UDP-galactose-dependent DGDG synthase, UDP-galactose-dependent digalactosyldiacylglycerol synthase, and UDP-galactose:MGDG galactosyltransferase. This enzyme participates in glycerolipid metabolism.
References
- Kelly AA, Dormann P . 2002 . DGD2, an arabidopsis gene encoding a UDP-galactose-dependent digalactosyldiacylglycerol synthase is expressed during growth under phosphate-limiting conditions . J. Biol. Chem. . 277 . 1166 - 73 . 11696551 . 10.1074/jbc.M110066200 . 2 . free .
- Hartel H, Dormann P, Benning C . 2000 . DGD1-independent biosynthesis of extraplastidic galactolipids after phosphate deprivation in Arabidopsis . Proc. Natl. Acad. Sci. U.S.A. . 97 . 10649 - 54 . 10973486 . 10.1073/pnas.180320497 . 19 . 27079 . free .
- Kelly AA, Froehlich JE, Dormann P . 2003 . Disruption of the two digalactosyldiacylglycerol synthase genes DGD1 and DGD2 in Arabidopsis reveals the existence of an additional enzyme of galactolipid synthesis . Plant Cell . 15 . 2694 - 706 . 14600212 . 10.1105/tpc.016675 . 11 . 280572 .
- Benning C, Ohta H . 2005 . Three enzyme systems for galactoglycerolipid biosynthesis are coordinately regulated in plants . J. Biol. Chem. . 280 . 2397 - 400 . 15590685 . 10.1074/jbc.R400032200 . 4 . free .
