Diacylglycerol kinase (CTP dependent) explained

Diacylglycerol kinase (CTP dependent)
Ec Number:2.7.1.174

Diacylglycerol kinase (CTP dependent) (DAG kinase, CTP-dependent diacylglycerol kinase, diglyceride kinase) is an enzyme with systematic name CTP:1,2-diacyl-sn-glycerol 3-phosphotransferase.[1] [2] This enzyme catalyses the following chemical reaction

CTP + 1,2-diacyl-sn-glycerol

\rightleftharpoons

CDP + 1,2-diacyl-sn-glycerol 3-phosphate

This enzyme requires Ca2+ or Mg2+ for activity.

See also

Notes and References

  1. Han GS, O'Hara L, Carman GM, Siniossoglou S . An unconventional diacylglycerol kinase that regulates phospholipid synthesis and nuclear membrane growth . The Journal of Biological Chemistry . 283 . 29 . 20433–42 . July 2008 . 18458075 . 2459266 . 10.1074/jbc.m802903200 . free .
  2. Han GS, O'Hara L, Siniossoglou S, Carman GM . Characterization of the yeast DGK1-encoded CTP-dependent diacylglycerol kinase . The Journal of Biological Chemistry . 283 . 29 . 20443–53 . July 2008 . 18458076 . 2459283 . 10.1074/jbc.m802866200 . free .