Di-tert-butylzinc explained

Di-tert-butylzinc is a compound with the formula ZnC8H18. This compound is used as a meta activating reagent in the syntheses of N,N-dimethyl-3-iodoaniline from N,N-dimethylaniline.[1]

Synthesis

Di-tert-butylzinc is obtained from the reaction between tert-butyllithium and zinc chloride.

2 (CH3)3CLi + ZnCl2 → Zn(C(CH3)3)2 + 2 LiCl

Notes and References

  1. 10.1002/anie.200600720 . Directedmeta-Metalation Using Alkali-Metal-Mediated Zincation . 2006 . Armstrong . David R. . Clegg . William . Dale . Sophie H. . Hevia . Eva . Hogg . Lorna M. . Honeyman . Gordon W. . Mulvey . Robert E. . Angewandte Chemie International Edition . 45 . 23 . 3775–8. 16671139 . free .

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