Deoxylimonate A-ring-lactonase explained

deoxylimonate A-ring-lactonase
Ec Number:	3.1.1.46
Cas Number:	75788-82-8
Go Code:	0047845

The enzyme deoxylimonate A-ring-lactonase (EC 3.1.1.46) catalyzes the reaction

deoxylimonate + H₂O

\rightleftharpoons deoxylimononic acid D-ring-lactone

The reaction opens the A-ring-lactone of the triterpenoid deoxylimonic acid, leaving the D-ring-lactone intact.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is deoxylimonate A-ring-lactonohydrolase.

References

• Hasegawa H, Bennett RD, Verdon CP . 1980 . Metabolism of limonoids via a deoxylimonoid pathway in Citrus . . 19 . 1445 - 1447 . 10.1016/0031-9422(80)80191-9.