Dendroaspis natriuretic peptide explained

Dendroaspis natriuretic peptide (DNP) is a 38-residue peptide[1] and a member of natriuretic peptide family.[2] It is structurally similar to the atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP) and possesses biologic properties similar to these natriuretic peptides.

DNP was originally isolated from the venom of the green mamba snake (Dendroaspis angusticeps), from which its name is derived.

Notes and References

  1. Schweitz. Hugues. Vigne. Paul. Moinier. Danielle. Frelin. Christian. Lazdunski. Michel. 1992. A new member of the natriuretic peptide family is present in the venom of the green mamba (Dendroaspis angusticeps). The Journal of Biological Chemistry. 267. 20. 13928–13932. 10.1016/S0021-9258(19)49658-0. 1352773. free.
  2. Park. Seon-Ah. Kim. Tae-Geun. Han. Myung-Kwan. Ha. Ki-Chan. Kim. Sung-Zoo. Kwak. Yong-Geun. June 2012. Dendroaspis natriuretic peptide regulates the cardiac L-type Ca 2+ channel activity by the phosphorylation of α 1c proteins. Experimental & Molecular Medicine. en. 44. 6. 363–368. 10.3858/emm.2012.44.6.041. 2092-6413. 3389074. 22366884.

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