Demethylspheroidene O-methyltransferase explained

Demethylspheroidene O-methyltransferase
Ec Number:	2.1.1.210

Demethylspheroidene O-methyltransferase (1-hydroxycarotenoid O-methylase, 1-hydroxycarotenoid methylase, 1-HO-carotenoid methylase, CrtF) is an enzyme with systematic name S-adenosyl-L-methionine:demethylspheroidene O-methyltransferase.^{[1] [2] [3]} This enzyme catalyses the following chemical reaction

\rightleftharpoons S-adenosyl-L-homocysteine + spheroidene

In Rhodopseudomonas capsulata and Rubrivivax gelatinosus the enzyme is involved in biosynthesis of spheroidene.

Notes and References

1. Badenhop F, Steiger S, Sandmann M, Sandmann G . Expression and biochemical characterization of the 1-HO-carotenoid methylase CrtF from Rhodobacter capsulatus . FEMS Microbiology Letters . 222 . 2 . 237–42 . May 2003 . 12770713 . 10.1016/s0378-1097(03)00302-1 . free .
2. Pinta V, Ouchane S, Picaud M, Takaichi S, Astier C, Reiss-Husson F . Characterization of unusual hydroxy- and ketocarotenoids in Rubrivivax gelatinosus: involvement of enzyme CrtF or CrtA . Archives of Microbiology . 179 . 5 . 354–62 . May 2003 . 12664193 . 10.1007/s00203-003-0538-3 . 30048505 .
3. Scolnik PA, Walker MA, Marrs BL . Biosynthesis of carotenoids derived from neurosporene in Rhodopseudomonas capsulata . The Journal of Biological Chemistry . 255 . 6 . 2427–32 . March 1980 . 10.1016/S0021-9258(19)85909-4 . 7358679 . free .