Cytopenia is a reduction in the number of mature blood cells. It can have many causes, and commonly occurs in people with cancer being treated with radiation therapy or chemotherapy.
There are also two general causes of cytopenia: autoimmune and refractory. Autoimmune cytopenia is caused by an autoimmune disease when your body produces antibodies to destroy the healthy blood cells. Refractory cytopenia is caused by bone marrow not producing healthy blood cells, and can be a result of cancer.
The symptoms of cytopenia vary depending on the type.
The symptoms of anemia include:
The symptoms of leukopenia include:
The symptoms of thrombocytopenia include:
Cytopenias can be caused by anything that decreases the production of blood cells or increases the destruction of blood cells. This includes, but is not limited to:
The treatments for cytopenia vary depending on the type of cytopenia. The treatment for anemia is rest and a diet consisting of high iron foods. Medication can also be used such as:
People with thrombocytopenia are advised to avoid contact with people who are ill, monitor closely for signs of infection, and take antibiotics when appropriate.
Bone marrow and stem cell transplantation are effective for all types of cytopenias. However, when a compatible donor cannot be found, immunosuppressive therapy is also common. Antilymphocyte globulin (ALG) or antithymocyte globulin (ATG) is mixed with cyclosporine to promote cell growth. [5]