Cysteinyldopa Explained

Cysteinyldopa is a catecholamine. Excessive cysteinyldopa in plasma and urine has been linked to malignant melanoma.^{[1] [2]} Cysteinyldopa is found in large amounts in the plasma and urine of patients with malignant melanoma. It is therefore used in the diagnosis of melanoma and for the detection of postoperative metastases. Cysteinyldopa is believed to be formed by the rapid enzymatic hydrolysis of 5-S-glutathionedopa found in melanin-producing cells.

See also

• L-DOPA
• D-DOPA

Notes and References

1. Acta Derm Venereol . 1979 . 59 . 5 . 381–388 . 5 years' experience of 5-S-cysteinyldopa in melanoma diagnosis . Agrup G, Agrup P, Andersson T, Hafström L, Hansson C, Jacobsson S, Jönsson PE, Rorsman H, Rosengren AM, Rosengren E . 93360.
2. Jpn J Ophthalmol . 2001 . 45 . 5 . 538–542 . 5-S-cysteinyldopa as diagnostic tumor marker for uveal malignant melanoma . Goto H, Usui M, Wakamatsu K, Ito S . 10.1016/s0021-5155(01)00393-8 . 11583680.