Cyclopentanol dehydrogenase explained

cyclopentanol dehydrogenase
Ec Number:	1.1.1.163
Cas Number:	37364-12-8
Go Code:	0055041

In enzymology, a cyclopentanol dehydrogenase is an enzyme that catalyzes the chemical reaction

cyclopentanol + NAD⁺

\rightleftharpoons cyclopentanone + NADH + H⁺

Thus, the two substrates of this enzyme are cyclopentanol and NAD⁺, whereas its 3 products are cyclopentanone, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is cyclopentanol:NAD⁺ oxidoreductase.

References

• Griffin M, Trudgill PW . 1972 . The metabolism of cyclopentanol by Pseudomonas N.C.I.B. 9872 . Biochem. J. . 129 . 595 - 603 . 4349113 . 3 . 1174162 .
• Iwaki H, Hasegawa Y, Wang S, Kayser MM, Lau PC . 2002 . Cloning and characterization of a gene cluster involved in cyclopentanol metabolism in Comamonas sp. strain NCIMB 9872 and biotransformations effected by Escherichia coli-expressed cyclopentanone 1,2-monooxygenase . Appl. Environ. Microbiol. . 68 . 5671 - 84 . 12406764 . 10.1128/AEM.68.11.5671-5684.2002 . 11 . 129933 .