Cyclooctanone Explained

Cyclooctanone is an organic compound with the formula . It is a waxy white solid.

Synthesis and reactions

It can be prepared by

• Jones oxidation or Dess-Martin oxidation of cyclooctanol.^[1]
• ketonization reaction starting with azelaic acid.^[2]

Among its many reactions, Baeyer-Villiger oxidation gives the nine-membered cyclic ester.^[3]

See also

• Suberone

Notes and References

1. 10.1021/ja00019a027 . A useful 12-I-5 triacetoxyperiodinane (The Dess-Martin periodinane) for the selective oxidation of primary or secondary alcohols and a variety of related 12-I-5 species . 1991 . Dess . Daniel B. . Martin . J. C. . Journal of the American Chemical Society . 113 . 19 . 7277–7287 .
2. E. J. Eisenbraun. 10.15227/orgsyn.045.0028. Cycloöctanone . Organic Syntheses . 1965 . 45 . 28 .
3. Book: 10.1002/0471264180.or043.03 . TheBaeyer–VilligerOxidation of Ketones and Aldehydes . Organic Reactions . 1993 . Krow . Grant R. . 251–798 . 978-0-471-26418-7 .