Cycloisomaltooligosaccharide glucanotransferase explained

Cycloisomaltooligosaccharide glucanotransferase
Ec Number:2.4.1.248

Cycloisomaltooligosaccharide glucanotransferase is an enzyme with systematic name (1->6)-alpha-D-glucan:(1->6)-alpha-D-glucan 6-alpha-D-(1->6alpha-D-glucano)-transferase (cyclizing).[1] [2] [3] This enzyme catalyses the following chemical reaction

cyclizes part of a (1->6)-alpha-D-glucan chain by formation of a (1->6)-alpha-D-glucosidic bond

This enzyme is specific for (1->6)-alpha-D-glucans (dextrans).

Notes and References

  1. Novel Cyclic dextrins, Cycloisomaltooligosaccharides, from Bacillus sp. T-3040 culture . Oguma T, Horiuchi T, Kobayashi M . Biosci. Biotechnol. Biochem. . 1993 . 57 . 1225–1227 . 27281012. 10.1271/bbb.57.1225. free .
  2. Purification and properties of a novel enzyme from Bacillus spp. T-3040, which catalyzes the conversion of dextran to cyclic isomaltooligosaccharides . Oguma, T. . Tobe, K. . Kobayashi, M. . amp . FEBS Lett. . 1994 . 345 . 135–138 . 7515357 . 10.1016/0014-5793(94)00418-8. free .
  3. Identification of catalytic amino acids of cyclodextran glucanotransferase from Bacillus circulans T-3040 . Yamamoto, T. . Terasawa, K. . Kim, Y.M. . Kimura, A. . Kitamura, Y. . Kobayashi, M. . Funane, K. . amp . Biosci. Biotechnol. Biochem. . 2006 . 70 . 1947–1953 . 16926507 . 10.1271/bbb.60105. free .