Cyclododecanone Explained

Cyclododecanone is an organic compound with the formula (CH₂)₁₁CO. It is a cyclic ketone that exists as a white solid at room temperature.

Synthesis

It is produced by the oxidation of cyclododecane via cyclododecanol.^[1]

Uses

• Cyclododecanone is mainly consumed as a precursor to 1,12-dodecanedioic acid and laurolactam, which are precursors to certain specialized nylons.
• Small amounts are also converted to cyclohexadecanone, which is used in some fragrances.^[2]

Drug Use

Hydrazone formation with pimagedine leads to a hypoglycemic formula.^[3] Notice that the shape of the molecule can be made to appear like a pharmacy cross symbol.

Notes and References

1. Schiffer, T.; Oenbrink, G. "Cyclododecanol, Cyclododecanone, and Laurolactam" in Ullman’s Encyclopedia of Industrial Chemistry: Wiley-VCH, 2009.
2. Johannes Panten and Horst Surburg "Flavors and Fragrances, 2. Aliphatic Compounds" in Ullmann's Encyclopedia of Industrial Chemistry, 2015, Wiley-VCH, Weinheim.
3. J Nordmann, et al. (1973 to Ugine Kuhlmann SA).