Curvularin Explained

Curvularin is an antimicrobial chemical compound produced by Penicillium and Curvularia.^[1]

Characteristics

!Characteristic!Value

Number of hydrogen bond acceptors	5
Number of hydrogen bond donors	2
Number of rotating bonds	0
Partition coefficient^[2] (ALogP)	3.0
Solubility^[3] (logS, log(mol/L))	-2.8
Polar surface area^[4] (PSA, Å2)	83.8

External links

• Fermentek Curvularin

Notes and References

1. Savchuk . IaI . Zaĭchenko . AM . Tsyganenko . ES . Biological activity of Penicillium sp. 10-51 exometabolites . Mikrobiolohichnyi Zhurnal . July 2012 . 74 . 4 . 52–6 . 23088100.
2. 10.1021/jp980230o . Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragmental Methods: An Analysis of ALOGP and CLOGP Methods . 1998 . Ghose . Arup K. . Viswanadhan . Vellarkad N. . Wendoloski . John J. . The Journal of Physical Chemistry A . 102 . 21 . 3762–3772 . 1998JPCA..102.3762G .
3. Ghose . Arup K. . Viswanadhan . Vellarkad N. . Wendoloski . John J. . 1998-05-01 . Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragmental Methods: An Analysis of ALOGP and CLOGP Methods . The Journal of Physical Chemistry A . en . 102 . 21 . 3762–3772 . 10.1021/jp980230o . 1998JPCA..102.3762G . 1089-5639.
4. Ertl . Peter . Rohde . Bernhard . Selzer . Paul . 2000-10-01 . Fast Calculation of Molecular Polar Surface Area as a Sum of Fragment-Based Contributions and Its Application to the Prediction of Drug Transport Properties . Journal of Medicinal Chemistry . en . 43 . 20 . 3714–3717 . 10.1021/jm000942e . 11020286 . 0022-2623.