Crotonyl-CoA reductase explained

Crotonyl-CoA reductase
Ec Number:	1.3.1.86

Crotonyl-CoA reductase (butyryl-CoA dehydrogenase, butyryl dehydrogenase, unsaturated acyl-CoA reductase, ethylene reductase, enoyl-coenzyme A reductase, unsaturated acyl coenzyme A reductase, butyryl coenzyme A dehydrogenase, short-chain acyl CoA dehydrogenase, short-chain acyl-coenzyme A dehydrogenase, 3-hydroxyacyl CoA reductase, butanoyl-CoA:(acceptor) 2,3-oxidoreductase, CCR) is an enzyme with systematic name butanoyl-CoA:NADP⁺ 2,3-oxidoreductase.^[1] This enzyme catalyses the following chemical reaction

butanoyl-CoA + NADP⁺

\rightleftharpoons (E)-but-2-enoyl-CoA + NADPH + H⁺

This enzyme catalyses the reaction in the reverse direction.

Notes and References

1. Wallace KK, Bao ZY, Dai H, Digate R, Schuler G, Speedie MK, Reynolds KA . Purification of crotonyl-CoA reductase from Streptomyces collinus and cloning, sequencing and expression of the corresponding gene in Escherichia coli . European Journal of Biochemistry . 233 . 3 . 954–62 . November 1995 . 8521864 . 10.1111/j.1432-1033.1995.954_3.x . free .