Crocetin glucosyltransferase explained

Crocetin glucosyltransferase
Ec Number:	2.4.1.271

Crocetin glucosyltransferase (crocetin GTase, UGTCs2) is an enzyme with systematic name UDP-glucose:crocetin 8-O-D-glucosyltransferase.^{[1] [2]} This enzyme catalyses the following chemical reaction

(1) UDP-glucose + crocetin

\rightleftharpoons UDP + beta-D-glucosyl crocetin

(2) UDP-glucose + beta-D-glucosyl crocetin

\rightleftharpoons UDP + bis(beta-D-glucosyl) crocetin

(3) UDP-glucose + beta-D-gentiobiosyl crocetin

\rightleftharpoons UDP + beta-D-gentiobiosyl beta-D-glucosyl crocetin

In Crocus sativus this enzyme esterifies a free carboxyl group of crocetin or crocetin glycosyl ester.

Notes and References

1. Properties of a glucosyltransferase involved in crocin synthesis . Côté F, Cormier F, Dufresne C, Willemot C . Plant Sci. . 2000 . 153 . 55–63 . 10.1016/S0168-9452(99)00248-4 .
2. Moraga AR, Nohales PF, Pérez JA, Gómez-Gómez L . Glucosylation of the saffron apocarotenoid crocetin by a glucosyltransferase isolated from Crocus sativus stigmas . Planta . 219 . 6 . 955–66 . October 2004 . 15605174 . 10.1007/s00425-004-1299-1 .