Cortivazol Explained

Cortivazol is a high-affinity agonist ligand for the glucocorticoid receptor and consequently is classified as a glucocorticoid.[1]

It is sometimes abbreviated "CVZ".[2]

Notes and References

  1. Schlechte JA, Simons SS, Lewis DA, Thompson EB . [3H]cortivazol: a unique high affinity ligand for the glucocorticoid receptor . Endocrinology . 117 . 4 . 1355–62 . October 1985 . 4029081 . 10.1210/endo-117-4-1355. free .
  2. Yoshikawa N, Yamamoto K, Shimizu N, Yamada S, Morimoto C, Tanaka H . The distinct agonistic properties of the phenylpyrazolosteroid cortivazol reveal interdomain communication within the glucocorticoid receptor . Mol. Endocrinol. . 19 . 5 . 1110–24 . May 2005 . 15677712 . 10.1210/me.2004-0264 . free .

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